Effectiveness of home treatment in children and adolescents with psychiatric disorders-systematic review and meta-analysis.

Graf, Daniel; Sigrist, Christine; Boege, Isabel; Cavelti, Marialuisa; Koenig, Julian; Kaess, Michael (2024). Effectiveness of home treatment in children and adolescents with psychiatric disorders-systematic review and meta-analysis. BMC medicine, 22(1), p. 241. BioMed Central 10.1186/s12916-024-03448-2

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BACKGROUND

Home treatment in child and adolescent psychiatry offers an alternative to conventional inpatient treatment by involving the patient's family, school, and peers more directly in therapy. Although several reviews have summarised existing home treatment programmes, evidence of their effectiveness remains limited and data synthesis is lacking.

METHODS

We conducted a meta-analysis on the effectiveness of home treatment compared with inpatient treatment in child and adolescent psychiatry, based on a systematic search of four databases (PubMed, CINAHL, PsychINFO, Embase). Primary outcomes were psychosocial functioning and psychopathology. Additional outcomes included treatment satisfaction, duration, costs, and readmission rates. Group differences were expressed as standardised mean differences (SMD) in change scores. We used three-level random-effects meta-analysis and meta-regression and conducted both superiority and non-inferiority testing.

RESULTS

We included 30 studies from 13 non-overlapping samples, providing data from 1795 individuals (mean age: 11.95 ± 2.33 years; 42.5% female). We found no significant differences between home and inpatient treatment for postline psychosocial functioning (SMD = 0.05 [- 0.18; 0.30], p = 0.68, I2 = 98.0%) and psychopathology (SMD = 0.10 [- 0.17; 0.37], p = 0.44, I2 = 98.3%). Similar results were observed from follow-up data and non-inferiority testing. Meta-regression showed better outcomes for patient groups with higher levels of psychopathology at baseline and favoured home treatment over inpatient treatment when only randomised controlled trials were considered.

CONCLUSIONS

This meta-analysis found no evidence that home treatment is less effective than conventional inpatient treatment, highlighting its potential as an effective alternative in child and adolescent psychiatry. The generalisability of these findings is reduced by limitations in the existing literature, and further research is needed to better understand which patients benefit most from home treatment.

TRIAL REGISTRATION

Registered at PROSPERO (CRD42020177558), July 5, 2020.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy

UniBE Contributor:

Graf, Daniel, Cavelti, Marialuisa (A), Kaess, Michael

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1741-7015

Publisher:

BioMed Central

Language:

English

Submitter:

Pubmed Import

Date Deposited:

13 Jun 2024 14:07

Last Modified:

16 Aug 2024 10:25

Publisher DOI:

10.1186/s12916-024-03448-2

PubMed ID:

38867231

Uncontrolled Keywords:

Child and adolescent psychiatry Home treatment Meta-analysis Treatment research Treatment setting

BORIS DOI:

10.48350/197803

URI:

https://boris.unibe.ch/id/eprint/197803

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