Peros, Ioannis; Haneke, Eckart (2024). Fibrotic reaction to hyaluronic acid fillers in the face. Journal of cosmetic dermatology, 23(8), pp. 2543-2546. Wiley 10.1111/jocd.16419
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J_of_Cosmetic_Dermatology_-_2024_-_Peros_-_Fibrotic_reaction_to_hyaluronic_acid_fillers_in_the_face.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (2MB) | Preview |
BACKGROUND
Hyaluronic acids (HAs) can have very different actions not only depending on injector and host factors but also depending on their molecular weight. Whereas short chain HA has immunological activity long chain HA influences fibroblasts and may stimulate them to produce collagen. Although this is generally thought to be a positive feature it may be disadvantageous in certain localizations.
PATIENTS AND METHODS
We have encountered 23 patients who developed fibrous tissue next to the nasolabial folds accentuating them and becoming very obvious while smiling. Hyaluronidase injection did not reduce this mass.
RESULTS
Intralesional triamcinolone acetonide injection led to rapid improvement.
DISCUSSION
Fibrotic tissue reaction not responding to hyaluronidase may be the result of HA injection and can effectively be treated with intralesional steroid injection.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Haneke, Eckart |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1473-2165 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
20 Jun 2024 08:46 |
Last Modified: |
26 Jul 2024 00:15 |
Publisher DOI: |
10.1111/jocd.16419 |
PubMed ID: |
38890804 |
Uncontrolled Keywords: |
body dysmorphic disorder dermal filler fibroblasts hyaluronic acid nasolabial fold |
BORIS DOI: |
10.48350/197956 |
URI: |
https://boris.unibe.ch/id/eprint/197956 |
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