Autotransplantation with Adjunctive Application of Enamel Matrix Derivatives Using a Digital Workflow: A Prospective Case Series.

Pedrinaci, Ignacio; Calatrava, Javier; Couso Queiruga, Emilio; Bethencourt, Juan Del Rosal; Sanz-Sanchez, Ignacio; Gallucci, German O; Sanz, Mariano (2024). Autotransplantation with Adjunctive Application of Enamel Matrix Derivatives Using a Digital Workflow: A Prospective Case Series. Journal of dentistry, 148(105131), p. 105131. Elsevier Science 10.1016/j.jdent.2024.105131

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OBJECTIVES

Digital protocols and bioactive materials may reduce complications and improve tooth autotransplantation (ATT) success and survival rates. This prospective study assesses the performance of a fully digital autotransplantation protocol of close-apex molars with the adjunctive application of Enamel Matrix Derivatives (EMD).

METHODS

Twelve adult patients with 13 hopeless molar teeth were replaced with autotransplantation of closed apex third molars. Outcomes, including success and survival rates, clinical, endodontic, radiographic, patient-reported outcome measures (PROMs), and digital image assessments, were conducted over a two-year follow-up period.

RESULTS

Survival and success rates were 100% and 91.2%, respectively, with no progressive inflammatory or replacement root resorption (ankylosis) except for one tooth presenting radiographic furcation involvement. A significant probing depth reduction of 2.4 ± 2.58 mm and CAL gains of 2.8 ± 3.03 mm were observed in transplanted teeth compared to the hopeless receptor teeth. Radiographic bone levels remained stable throughout the study period (-0.37 ± 0.66 mm), and digital image assessments showed minimal alveolar ridge width changes (-0.32 to -0.7 mm) and gingival margin changes (-0.95 to -1.27 mm) from baseline to last visit. PROMs indicated very high patient satisfaction.

CONCLUSION

The use of a digital ATT protocol with adjunctive use of EMD in closed-apex third molars demonstrated promising short-term high success and survival rates. Additionally, this type of therapy adequately preserves the dimensions of the alveolar ridge in the receptor site.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Oral Surgery and Stomatology

UniBE Contributor:

Couso-Queiruga, Emilio

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0300-5712

Publisher:

Elsevier Science

Language:

English

Submitter:

Pubmed Import

Date Deposited:

02 Jul 2024 10:11

Last Modified:

13 Aug 2024 00:15

Publisher DOI:

10.1016/j.jdent.2024.105131

PubMed ID:

38950765

Uncontrolled Keywords:

(MeSHterms) Tooth Autotransplantation Autologous Transplantation Case series Computer-Assisted Surgery EMDOGAIN Enamel Matrix Derivatives

BORIS DOI:

10.48350/198355

URI:

https://boris.unibe.ch/id/eprint/198355

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