Breast cancer and human papillomavirus (HPV) infection: No evidence of a viral etiology in a group of Swiss women

Lindel, Katja; Forster, Andrea; Altermatt, Hans J; Greiner, Richard; Gruber, Guenther (2007). Breast cancer and human papillomavirus (HPV) infection: No evidence of a viral etiology in a group of Swiss women. Breast, 16(2), pp. 172-7. Amsterdam: Elsevier 10.1016/j.breast.2006.09.001

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There are controversial data on the meaning of viral induction of breast cancer. The aim of this study was to investigate the presence of human papillomavirus (HPV) DNA in patients with breast carcinoma and the correlation of viral infection with disease outcome. Paraffin-embedded sections from 81 patients with breast cancer were analyzed for HPV DNA by polymerase chain reaction (PCR) using the SPF1/2 primers covering about 40 different low-, intermediate- and high-risk types. We found all samples were negative for HPV DNA. Our analysis could not support a role of HPV in breast carcinoma. Controversial published data indicate a need for further, larger epidemiologic studies.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology
UniBE Contributor:	Greiner, Richard
ISSN:	0960-9776
ISBN:	17088061
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:48
Last Modified:	05 Dec 2022 14:14
Publisher DOI:	10.1016/j.breast.2006.09.001
PubMed ID:	17088061
Web of Science ID:	000257273800011
URI:	https://boris.unibe.ch/id/eprint/19938 (FactScience: 3016)