Alterations of the thoracic spine in Marfan's syndrome

Daeubler, Bernd F; Carrel, Thierry; Kujawski, Tomasz; Schnyder, Aurelia; Zurmuehle, Pia; Vock, Peter; Anderson, Suzanne E (2006). Alterations of the thoracic spine in Marfan's syndrome. AJR, American journal of roentgenology, 186(5), pp. 1246-51. Leesburg, Va.: American Roentgen Ray Society 10.2214/AJR.05.0071

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OBJECTIVE: The purpose of this study was to determine if the thoracic vertebral elements are altered in patients with Marfan's syndrome. MATERIALS AND METHODS: Thirty patients underwent helical CT of the thorax because of suspected thoracic aortic dilatation and acute dissection. Thirteen had Marfan's syndrome and 17 did not. Two reviewers, unaware of the final diagnosis, evaluated the images by consensus for laminar thickness, foraminal width, dural sac ratios, and vertebral scalloping for T2-T12. RESULTS: At T9-T12, dural sac ratios at the midcorpus level (p = 0.031) and foraminal width (p = 0.0124) were significantly greater in the patients with Marfan's syndrome than in the patients without. Dural sac ratios at lower endplate levels (p = 0.0685), laminar thickness (p = 0.951), and vertebral scalloping (p = 0.24) were not significantly greater in the patients with Marfan's syndrome than in the patients without. CONCLUSION: Because the phenotypic expression of Marfan's syndrome is variable, information on the spine from thoracic studies in combination with major criteria may be helpful clinically.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Carrel, Thierry and Vock, Peter

ISSN:

0361-803X

ISBN:

16632713

Publisher:

American Roentgen Ray Society

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:48

Last Modified:

17 Mar 2015 21:48

Publisher DOI:

10.2214/AJR.05.0071

PubMed ID:

16632713

Web of Science ID:

000237003300008

URI:

https://boris.unibe.ch/id/eprint/19977 (FactScience: 3056)

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