Neuropsychological problems after paediatric stroke: two year follow-up of Swiss children

Pavlovic, J; Kaufmann, F; Boltshauser, E; Capone Mori, A; Gubser Mercati, D; Haenggeli, C-A; Keller, E; Lütschg, J; Marcoz, J-P; Ramelli, G-P; Roulet Perez, E; Schmitt-Mechelke, T; Weissert, M; Steinlin, M (2006). Neuropsychological problems after paediatric stroke: two year follow-up of Swiss children. Neuropediatrics, 37(1), pp. 13-9. Stuttgart: Hippokrates Verlag 10.1055/s-2006-923932

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AIM: The aim of this study was to obtain information about neurological and cognitive outcome for a population-based group of children after paediatric ischaemic stroke. METHODS: Data from the Swiss neuropaediatric stroke registry (SNPSR), from 1.1.2000 to 1.7.2002, including children (AIS 1) and neonates (AIS 2). At 18-24 months after a stroke, a follow-up examination was performed including a history, neurological and neuropsychological assessment. RESULTS: 33/48 children (22 AIS 1, 11 AIS 2) participated in the study. Neurological outcome was good in 16/33. After childhood stroke mean IQ levels were normal (94), but 6 children had IQ < 85 (50-82) and neuropsychological problems were present in 75%. Performance IQ (93) was reduced compared to verbal IQ (101, p = 0.121) due to problems in the domain of processing speed (89.5); auditory short-term memory was especially affected. Effects on school career were common. Outcome was worse in children after right-sided infarction. Children suffering from stroke in mid-childhood had the best prognosis. There was no clear relationship between outcome and localisation of the lesion. After neonatal stroke 7/11 children showed normal development and epilepsy indicated a worse prognosis in the remaining 4. CONCLUSION: After paediatric stroke neuropsychological problems are present in about 75% of children. Younger age at stroke as well as an emergence of epilepsy were predictors for worse prognosis.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
UniBE Contributor:	Pavlovic, Julia, Steinlin, Maja
ISSN:	0174-304X
ISBN:	16541363
Publisher:	Hippokrates Verlag
Language:	English
Submitter:	Anette van Dorland
Date Deposited:	04 Oct 2013 14:48
Last Modified:	05 Dec 2022 14:14
Publisher DOI:	10.1055/s-2006-923932
PubMed ID:	16541363
Web of Science ID:	000236810800003
URI:	https://boris.unibe.ch/id/eprint/19995 (FactScience: 3074)