Biphosphonate-associated osteonecrosis of the maxilla. Case report and review of the literature

Bornstein, Michael; Oberli, Kaspar; Stauffer, Edouard; Buser, Daniel (2006). Biphosphonate-associated osteonecrosis of the maxilla. Case report and review of the literature. Schweizerische Monatsschrift für Zahnmedizin, 116(10), pp. 1035-47. Bern: Schweizerische Zahnärzte-Gesellschaft

[img]
Preview
Text
smfz-10-praxis2.pdf - Published Version
Available under License BORIS Standard License.

Download (187kB) | Preview
[img]
Preview
Text
f-smfz-10-praxis2.pdf - Published Version
Available under License BORIS Standard License.

Download (75kB) | Preview

In recent years, a growing number of reports in the literature have linked osteonecrosis of the jaw bones with intravenously administered bisphosphonates prescribed for the treatment of hypercalcemia of malignancy due to bone lesions of multiple myeloma or bone metastases in patients with breast or prostate cancer. Furthermore, an association between chronic oral bisphosphonate use in patients with osteoporosis or Paget's disease, and bone necrosis in the mandible or maxilla has been demonstrated in numerous case reports and case series in the last couple of years. Therapeutically, osteonecrosis of the jaws seems to be difficult to treat surgically, often resulting in a recurring or even progressing lesion. In the present case report of a bisphosphonate-associated osteonecrosis of the maxilla in a patient with osteoporosis, the current literature will be discussed, and open research questions and potential problems for our daily dental practice routine will be addressed.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Oral Surgery and Stomatology

UniBE Contributor:

Bornstein, Michael; Oberli, Kaspar and Buser, Daniel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0256-2855

Publisher:

Schweizerische Zahnärzte-Gesellschaft

Language:

Multilingual

Submitter:

Eveline Carmen Schuler

Date Deposited:

04 Oct 2013 14:48

Last Modified:

25 Jan 2017 12:17

PubMed ID:

17078515

BORIS DOI:

10.7892/boris.20015

URI:

https://boris.unibe.ch/id/eprint/20015 (FactScience: 3095)

Actions (login required)

Edit item Edit item
Provide Feedback