Subsecond fluorine-19 MRI of the lung

Wolf, Ursula; Scholz, Alexander; Heussel, Claus Peter; Markstaller, Klaus; Schreiber, Wolfgang Günther (2006). Subsecond fluorine-19 MRI of the lung. Magnetic resonance in medicine, 55(4), pp. 948-51. New York, N.Y.: Wiley-Liss 10.1002/mrm.20859

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Minimal scan times in rapid fluorine-19 MRI using sulfur hexafluoride (SF6) have been on the order of 10 s. Because of the very short T1 relaxation time of SF6 (T1 = 1.65 ms), high receiver bandwidths are necessary to allow for a high number of excitations. Since high bandwidths cause high levels of electronic noise, SNR per acquisition has been too low to further reduce scan time. The purpose of this study was to investigate whether scan times could be reduced using hexafluoroethane (C2F6), a gas with a longer T1 (T1 = 7.9 ms) at a relatively low bandwidth of 488 Hz/pixel. Gradient-echo images were acquired during and after completion of the wash-in of a 70% C2F6- 30% O2 mixture. Peak SNR values of 16 and 7.9 were observed for coronal projection images acquired within 2 s and 260 ms, respectively. These results demonstrate that subsecond imaging is feasible using C2F6.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy
UniBE Contributor:	Markstaller, Klaus Michael
ISSN:	0740-3194
ISBN:	16534836
Publisher:	Wiley-Liss
Language:	English
Submitter:	Jeannie Wurz
Date Deposited:	04 Oct 2013 14:49
Last Modified:	05 Dec 2022 14:15
Publisher DOI:	10.1002/mrm.20859
PubMed ID:	16534836
Web of Science ID:	000236602700031
URI:	https://boris.unibe.ch/id/eprint/20433 (FactScience: 3730)