Effects of somatosensory stimulation on use-dependent plasticity in chronic stroke

Sawaki, Lumy; Wu, Carolyn W-H; Kaelin-Lang, Alain; Cohen, Leonardo G (2006). Effects of somatosensory stimulation on use-dependent plasticity in chronic stroke. Stroke, 37(1), pp. 246-7. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/01.STR.0000195130.16843.ac

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BACKGROUND AND PURPOSE: There is a need to develop strategies to enhance the beneficial effects of motor training, including use-dependent plasticity (UDP), in neurorehabilitation. Peripheral nerve stimulation (PNS) modulates motor cortical excitability in healthy humans and could influence training effects in stroke patients. METHODS: We compared the ability of PNS applied to the (1) arm, (2) leg, and (3) idle time to influence training effects in the paretic hand in 7 chronic stroke patients. The end point measure was the magnitude of UDP. RESULTS: UDP was more prominent with arm stimulation (increased by 22.8%) than with idle time (by 2.9%) or leg stimulation (by 6.4%). CONCLUSIONS: PNS applied to the paretic limb paired with motor training enhances training effects on cortical plasticity in stroke patients.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Kaelin, Alain

ISSN:

0039-2499

ISBN:

16322491

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:50

Last Modified:

17 Mar 2015 21:52

Publisher DOI:

10.1161/01.STR.0000195130.16843.ac

PubMed ID:

16322491

Web of Science ID:

000234148500051

URI:

https://boris.unibe.ch/id/eprint/20964 (FactScience: 4776)

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