[Possible genetic link between Darier's disease and depression : Review of the literature and case history.]

Bach, D R; Moggi, Franz; Müller, T J; Seifritz, E; Strik, W K; Wirtz, G (2007). [Possible genetic link between Darier's disease and depression : Review of the literature and case history.]. Nervenarzt, 78(1), pp. 81-84. Heidelberg: Springer-Medizin-Verlag 10.1007/s00115-006-2116-9

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Darier's disease is a rare, inherited autosomal dominant skin disorder caused by a mutation in the sarcoendoplasmatic reticulum calcium transporter (SERCA)-2-gene. In a number of pedigrees, Darier's disease closely relates with affective disorder. The most likely hypothesis for this is a susceptibility gene for affective disorder near the SERCA-2-gene. A 6.5-megabase region could be identified as a susceptibility locus. This region constitutes a susceptability locus also in affective disorder without Darier's disease. The underlying gene has not yet been identified.

Item Type:

 Journal Article (Review Article)

Division/Institute:

 04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Translational Research Center
07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Management
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > UPD Murtenstrasse

UniBE Contributor:

 Bach, Dominik, Moggi, Franz (A), Müller, Thomas (A), Seifritz, Erich, Strik, Werner, Wirtz, Gustav

Subjects:

 600 Technology > 610 Medicine & health

ISSN:

 0028-2804

ISBN:

 16786359

Publisher:

 Springer-Medizin-Verlag

Language:

 German

Submitter:

 Factscience Import

Date Deposited:

 04 Oct 2013 14:51

Last Modified:

 29 Mar 2023 23:32

Publisher DOI:

 10.1007/s00115-006-2116-9

PubMed ID:

 16786359

Web of Science ID:

 000244305000010

Uncontrolled Keywords:

 Morbus Darier · Keratosis follicularis · Depression · Affektive Erkrankungen ·Molekulargenetik

BORIS DOI:

 10.7892/boris.21507

URI:

 https://boris.unibe.ch/id/eprint/21507 (FactScience: 7280)

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