[Possible genetic link between Darier's disease and depression : Review of the literature and case history.]

Bach, D R; Moggi, Franz; Müller, T J; Seifritz, E; Strik, W K; Wirtz, G (2007). [Possible genetic link between Darier's disease and depression : Review of the literature and case history.]. Nervenarzt, 78(1), pp. 81-4. Heidelberg: Springer-Verlag; http://www.springer.de 10.1007/s00115-006-2116-9

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Darier's disease is a rare, inherited autosomal dominant skin disorder caused by a mutation in the sarcoendoplasmatic reticulum calcium transporter (SERCA)-2-gene. In a number of pedigrees, Darier's disease closely relates with affective disorder. The most likely hypothesis for this is a susceptibility gene for affective disorder near the SERCA-2-gene. A 6.5-megabase region could be identified as a susceptibility locus. This region constitutes a susceptability locus also in affective disorder without Darier's disease. The underlying gene has not yet been identified.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Translational Research Center
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Management
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > UPD Murtenstrasse

UniBE Contributor:

Bach, Dominik; Moggi, Franz; Müller, Thomas Jörg; Seifritz, Erich; Strik, Werner and Wirtz, Gustav

ISSN:

0028-2804

ISBN:

16786359

Publisher:

Springer-Verlag; http://www.springer.de

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:51

Last Modified:

23 Oct 2019 09:41

Publisher DOI:

10.1007/s00115-006-2116-9

PubMed ID:

16786359

Web of Science ID:

000244305000010

BORIS DOI:

10.7892/boris.21507

URI:

https://boris.unibe.ch/id/eprint/21507 (FactScience: 7280)

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