Peri-implant inflammation defined by the implant-abutment interface

Broggini, Nina; McManus, Linda M; Hermann, Joachim S; Medina, Raúl Uriel; Schenk, Robert Konrad; Buser, Daniel; Cochran, David L (2006). Peri-implant inflammation defined by the implant-abutment interface. Journal of dental research, 85(5), pp. 473-478. Thousand Oaks, Calif.: Sage 10.1177/154405910608500515

[img] Text
21590.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (621kB) | Request a copy

An implant-abutment interface at the alveolar bone crest is associated with sustained peri-implant inflammation; however, whether magnitude of inflammation is proportionally dependent upon interface position remains unknown. This study compared the distribution and density of inflammatory cells surrounding implants with a supracrestal, crestal, or subcrestal implant-abutment interface. All implants developed a similar pattern of peri-implant inflammation: neutrophilic polymorphonuclear leukocytes (neutrophils) maximally accumulated at or immediately coronal to the interface. However, peri-implant neutrophil accrual increased progressively as the implant-abutment interface depth increased, i.e., subcrestal interfaces promoted a significantly greater maximum density of neutrophils than did supracrestal interfaces (10,512 +/- 691 vs. 2398 +/- 1077 neutrophils/mm(2)). Moreover, inflammatory cell accumulation below the original bone crest was significantly correlated with bone loss. Thus, the implant-abutment interface dictates the intensity and location of peri-implant inflammatory cell accumulation, a potential contributing component in the extent of implant-associated alveolar bone loss.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Oral Surgery and Stomatology

UniBE Contributor:

Broggini, Nina; Schenk, Robert Konrad and Buser, Daniel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0022-0345

Publisher:

Sage

Language:

English

Submitter:

Eveline Carmen Schuler

Date Deposited:

04 Oct 2013 14:51

Last Modified:

25 Jan 2017 12:17

Publisher DOI:

10.1177/154405910608500515

PubMed ID:

16632764

Web of Science ID:

000237002100015

BORIS DOI:

10.7892/boris.21590

URI:

https://boris.unibe.ch/id/eprint/21590 (FactScience: 8024)

Actions (login required)

Edit item Edit item
Provide Feedback