Tuberculosis after initiation of antiretroviral therapy in low-income and high-income countries

Antiretroviral, Therapy in Low-Income Countries Collaboration of the Internation; Cohort Collaboration, ART; Brinkhof, MW; Egger, M; Boulle, A; May, M; Hosseinipour, M; Sprinz, E; Braitstein, P; Dabis, F; Reiss, P; Bangsberg, DR; Rickenbach, M; Miro, JM; Myer, L; Mocroft, A; Nash, D; Keiser, O; Pascoe, M; van der Borght, S; ... (2007). Tuberculosis after initiation of antiretroviral therapy in low-income and high-income countries. Clinical infectious diseases, 45(11), pp. 1518-21. Cary, N.C.: Oxford University Press 10.1086/522986

Full text not available from this repository. (Request a copy)

We examined the incidence of and risk factors for tuberculosis during the first year of highly active antiretroviral therapy in low-income (4540 patients) and high-income (22,217 patients) countries. Although incidence was much higher in low-income countries, the reduction in the incidence of tuberculosis associated with highly active antiretroviral therapy was similar: the rate ratio for months 7-12 versus months 1-3 was 0.48 (95% confidence interval, 0.36-0.64) in low-income countries and 0.36 (95% confidence interval, 0.26-0.50) in high-income countries. A low CD4 cell count at the start of therapy was the most important risk factor in both settings.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine

UniBE Contributor:

Brinkhof, Martin and Egger, Matthias

ISSN:

1058-4838

ISBN:

17990236

Publisher:

Oxford University Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:52

Last Modified:

04 May 2014 23:15

Publisher DOI:

10.1086/522986

PubMed ID:

17990236

Web of Science ID:

000251080800020

URI:

https://boris.unibe.ch/id/eprint/22112 (FactScience: 30456)

Actions (login required)

Edit item Edit item
Provide Feedback