Snake venom C-type lectins as tools in platelet research

Clemetson, KJ; Polgár, J; Clemetson, JM (1998). Snake venom C-type lectins as tools in platelet research. Platelets, 9(3-4), pp. 165-9. London: Informa Healthcare 10.1080/09537109876636

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The snake C-type lectins are a major group of proteins present in venoms that fold to a structure with similarities to classic C-type lectins. The loop that would be involved in calcium and sugar binding is truncated and heterodimers are linked by a disulphide bond and by swapping loop domains between the subunits. M any of these C-type lectins interact with platelet receptors to inhibit or induce platelet activation. The use of these C-type lectins to investigate platelet function is discussed and illustrated with specific examples.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Theodor Kocher Institute

UniBE Contributor:

Clemetson, Kenneth John

ISSN:

0953-7104

ISBN:

16793696

Publisher:

Informa Healthcare

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:52

Last Modified:

04 May 2014 23:15

Publisher DOI:

10.1080/09537109876636

PubMed ID:

16793696

Web of Science ID:

000074619000004

URI:

https://boris.unibe.ch/id/eprint/22186 (FactScience: 32224)

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