A mixed epithelial and stromal tumor of the kidney in a ringtail lemur (Lemur catta)

Müller, S; Oevermann, A; Wenker, C; Altermatt, H J; Robert, Nadia (2007). A mixed epithelial and stromal tumor of the kidney in a ringtail lemur (Lemur catta). Veterinary pathology, 44(2), pp. 243-6. Middleton, Wis.: American College of Veterinary Pathologists 10.1354/vp.44-2-243

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Primary renal tumors are rare neoplasms in nonhuman primates. This report describes a mixed epithelial and stromal tumor of the kidney (MESTK) in a 14.5-year-old female ringtail lemur. The well-demarcated, solid, and cystic mass was located in the pelvis of the left kidney and consisted histologically of both epithelial and mesenchymal components. The mesenchymal cells were arranged in fascicles around cysts lined by a well-differentiated epithelium. Neither the mesenchymal nor the epithelial parts showed significant nuclear atypia or mitotic figures. To our knowledge, only 1 similar case, classified as adenoleiomyofibromatous hamartoma, has been reported in a ringtail lemur. In humans this tumor affects predominantly perimenopausal women and can express estrogen and progesterone receptors. However, neither estrogen nor progesterone receptors could be identified by immunohistochemistry in the tumor of the present ringtail lemur. Therefore, a hormonal mechanism could not be demonstrated in this case.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Center for Fish and Wildlife Health (FIWI)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Animal Pathology
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Experimental Clinical Research

UniBE Contributor:

Müller, Stéphanie; Oevermann, Anna and Robert, Nadia

Subjects:

600 Technology > 630 Agriculture

ISSN:

0300-9858

Publisher:

American College of Veterinary Pathologists

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:53

Last Modified:

10 Jul 2014 14:06

Publisher DOI:

10.1354/vp.44-2-243

PubMed ID:

17317808

Web of Science ID:

000244705400019

URI:

https://boris.unibe.ch/id/eprint/22271 (FactScience: 33770)

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