Discovery of insertion element ISCfe1: a new tool for Campylobacter fetus subspecies differentiation

Abril, C; Vilei, E M; Brodard, I; Burnens, A; Frey, J; Miserez, R (2007). Discovery of insertion element ISCfe1: a new tool for Campylobacter fetus subspecies differentiation. Clinical microbiology and infection, 13(10), pp. 993-1000. Oxford: Blackwell Publishing 10.1111/j.1469-0691.2007.01787.x

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The species Campylobacter fetus is divided into the subspecies C. fetus subsp. venerealis (CFV) and C. fetus subsp. fetus (CFF). CFV is the causative agent of bovine genital campylobacteriosis, a highly contagious venereal disease that may lead to serious reproductive problems, including sterility and abortion. In contrast, CFF can be isolated from the gastrointestinal tract of a wide range of host species, is associated with abortion in sheep and cattle, and can also be isolated from local and systemic infections in humans. Despite differences in host and niche preferences, microbiological differentiation of the two subspecies of C. fetus is extremely difficult. This study describes the identification of a new insertion element, ISCfe1, which is present exclusively in CFV strains, with highly conserved specific ISCfe1 insertion sites. The results are useful for identification and differentiation of the two C. fetus subspecies and will help in understanding the evolution and pathogenesis of C. fetus.

Item Type:

Journal Article (Original Article)


05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology
05 Veterinary Medicine > Other Institutions > Teaching Staff, Vetsuisse Faculty

UniBE Contributor:

Abril Gaona, Carlos, Vilei, Edi, Brodard, Isabelle, Burnens, André, Frey, Joachim, Miserez, Raymond François




Blackwell Publishing




Factscience Import

Date Deposited:

04 Oct 2013 14:53

Last Modified:

05 Dec 2022 14:16

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URI: (FactScience: 34285)

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