Hepatic encephalomyelopathy in a calf with congenital portosystemic shunt (CPSS)

Marçal, Valéria Café; Oevermann, Anna; Bley, Tim; Pfister, Patrizia; Miclard, Julien (2008). Hepatic encephalomyelopathy in a calf with congenital portosystemic shunt (CPSS). Journal of veterinary science, 9(1), pp. 113-5. Seoul: The Korean Society of Veterinary Science

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A 4-month-old female Holstein Friesian calf was referred to the Veterinary Teaching Hospital, University of Berne, Switzerland for evaluation of ataxia, weakness, apathy and stunted growth. Clinical examination revealed generalized ataxia, propioceptive deficits, decreased menace response and sensibility. Postmortem examination did not reveal macroscopic changes of major organs. Histologically, the brain and the spinal cord lesions were characterized by polymicrocavitation, preferentially affecting the white matter fibers at the junction of grey and white matter and by the presence of Alzheimer type II cells. The liver revealed lesions consistent with a congenital portosystemic shunt, characterized by increased numbers of arteriolar profiles and hypoplasia to absence of portal veins. The pathological investigations along with the animal history and clinical signs indicated a hepatic encephalomyelopathy due to a congenital portosystemic shunt.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Animal Pathology
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Experimental Clinical Research
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Clinical Neurology
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Clinic for Ruminants

UniBE Contributor:

Café Marçal, Valéria, Oevermann, Anna, Bley, Tim Hendrik, Pfister, Patrizia, Miclard, Julien

ISSN:

1229-845X

Publisher:

The Korean Society of Veterinary Science

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:54

Last Modified:

05 Dec 2022 14:16

PubMed ID:

18296896

Web of Science ID:

000253787300016

URI:

https://boris.unibe.ch/id/eprint/22865 (FactScience: 37375)

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