Alcoholic liver disease in the elderly

Seitz, Helmut K; Stickel, Felix (2007). Alcoholic liver disease in the elderly. Clinics in geriatric medicine, 23(4), 905-21, viii. New York, N.Y.: Elsevier ScienceDirect 10.1016/j.cger.2007.06.010

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Although per capita alcohol consumption, and thus the prevalence of alcoholic liver disease, decreases generally with age in Europe and in the United States, recently an increase in alcohol consumption has been reported in individuals over 65 years. Reasons explaining this observation may include an increase in life expectancy or a loss of life partners and, thus, loneliness and depression. Although ethanol metabolism and ethanol distribution change with age, and an elderly person's liver is more susceptible to the toxic effect of ethanol, the spectrum of alcoholic liver diseases and their symptoms and signs is similar to that seen in patients of all ages. However, prognosis of alcoholic liver disease in the elderly is poor. In addition, chronic alcohol consumption may enhance drug associated liver disease and may also act as a cofactor in other liver diseases, such as viral hepatitis and nonalcoholic fatty liver disease.

Item Type:

Journal Article (Further Contribution)


04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Stickel, Felix






Elsevier ScienceDirect




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Date Deposited:

04 Oct 2013 14:54

Last Modified:

04 May 2014 23:15

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URI: (FactScience: 38065)

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