Outcome of elderly patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction

Wenaweser, Peter; Ramser, Marianne; Windecker, Stephan; Lütolf, Indira; Meier, Bernhard; Seiler, Christian; Eberli, Franz R; Hess, Otto M (2007). Outcome of elderly patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction. Catheterization and cardiovascular interventions, 70(4), pp. 485-90. Hoboken, N.J.: Wiley-Blackwell 10.1002/ccd.21128

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AIM: To investigate the outcome of primary percutaneous coronary interventions (PCI) in elderly patients (>/=>/=75 years) with ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS: Between 1995 and 2003, a total of 319 consecutive patients with acute ST-elevation myocardial infarction presenting within 6-12 hr after onset of symptoms were prospectively enrolled in a registry. Of 296 patients undergoing primary PCI, 40 patients were >/=>/=75 years old (group A) and 256 patients younger than 75 years (group B). Elderly patients presented with a lower ejection fraction (49 +/- 14% vs. 53 +/- 13%, P = 0.046) and a higher number of cardiovascular risk factors. PCI success was achieved in 80% (group A) and 91% (group B, P = 0.031), respectively with comparable door-to-balloon times (87 +/- 49 and 95 +/- 79 min, P = ns). Periprocedural complications in both groups were low and major adverse cardiac events (death, myocardial infarction, target vessel revascularization and cardiac rehospitalization) after 6 months amounted to 23% (group A) and 20% (group B, P = ns), respectively. CONCLUSIONS: Clinical outcome of elderly patients (>/=>/=75 years) with acute STEMI is favorable and comparable with the middle-aged population. However, procedural success was significantly lower in elderly (80%) compared to younger patients (90%). Acute percutaneous coronary intervention appears to be safe and not associated with higher periprocedural complications, in elderly patients.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Wenaweser, Peter Martin; Windecker, Stephan; Meier, Bernhard; Seiler, Christian; Eberli, Franz and Hess, Otto

ISSN:

1522-1946

ISBN:

17894363

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:54

Last Modified:

04 May 2014 23:16

Publisher DOI:

10.1002/ccd.21128

PubMed ID:

17894363

Web of Science ID:

000250104300002

URI:

https://boris.unibe.ch/id/eprint/23229 (FactScience: 40654)

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