Eberli, Franz R; Roffi, Marco (2007). [Treatment after drug-eluting stent placement]. Herz, 32(4), pp. 301-6. München: Springer-Medizin-Verlag 10.1007/s00059-007-3008-x
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The use of drug-eluting stents (DES) in percutaneous coronary interventions (PCI) decreased the rate of restenosis and hence the need for repeat revascularization by 50-71%. DES have changed PCI. DES allow successful revascularization of anatomically challenging lesions, such as long, thin vessels, bifurcation lesions, and chronic total occlusions. A rare, but severe complication of coronary stenting is stent thrombosis, a partial or total thrombotic occlusion of the stent. The use of DES for increasingly more complex lesions, the prothrombotic effect of the antiproliferative substances, and a delayed endothelialization of DES all potentially prolong and increase the risk of stent thrombosis. Dual antiplatelet therapy for 1 year is therefore recommended after DES placement. There is currently no evidence for the efficacy and safety of routine dual antiplatelet therapy beyond 1 year. It is also recommended postponing elective surgery for 1 year and, if surgery cannot be deferred, considering continuation of acetylsalicylic acid during the perioperative period in high-risk patients with DES.
Item Type: |
Journal Article (Further Contribution) |
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Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Eberli, Franz |
ISSN: |
0340-9937 |
ISBN: |
17607537 |
Publisher: |
Springer-Medizin-Verlag |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:55 |
Last Modified: |
05 Dec 2022 14:17 |
Publisher DOI: |
10.1007/s00059-007-3008-x |
PubMed ID: |
17607537 |
Web of Science ID: |
000249004800010 |
BORIS DOI: |
10.48350/23231 |
URI: |
https://boris.unibe.ch/id/eprint/23231 (FactScience: 40659) |