The impact of statin treatment on presentation mode and early outcomes in acute coronary syndromes

Cuculi, F; Radovanovic, D; Eberli, F R; Stauffer, J C; Bertel, O; Erne, P (2008). The impact of statin treatment on presentation mode and early outcomes in acute coronary syndromes. Cardiology, 109(3), pp. 156-62. Basel: Karger 10.1159/000106676

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OBJECTIVES: The role of statin use in the treatment of acute coronary syndromes (ACS) is not clear. The aim of our study was to evaluate the role of statins in ACS. METHODS: Using data from the Acute Myocardial Infarction in Switzerland (AMIS Plus) Project, we compared the effects of chronic statin use, statin therapy after admission and no statin therapy on presentation mode and outcomes in ACS. RESULTS: Available data from the period 2001-2006 including 11,603 patients were analyzed. Major cardiac event rates and in-hospital mortality were more common in statin-naive patients compared to patients who received statins. CONCLUSIONS: Our results support the importance of statin treatment in ACS. Chronic statin therapy seems to alter the initial presentation of ACS but it is questionable whether it provides an additional effect on early outcomes compared to the establishment of statin therapy after admission in statin-naive patients.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Eberli, Franz

ISSN:

0008-6312

ISBN:

17726316

Publisher:

Karger

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:55

Last Modified:

04 May 2014 23:16

Publisher DOI:

10.1159/000106676

PubMed ID:

17726316

Web of Science ID:

000251048400003

URI:

https://boris.unibe.ch/id/eprint/23238 (FactScience: 40674)

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