EEG reactivity and EEG activity in never-treated acute schizophrenics, measured with spectral parameters and dimensional complexity

Koukkou, M; Lehmann, D; Federspiel, A; Merlo, MC (1995). EEG reactivity and EEG activity in never-treated acute schizophrenics, measured with spectral parameters and dimensional complexity. Journal of neural transmission, 99(1-3), pp. 89-102. Wien: Springer 10.1007/BF01271472

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Our approaches to the use of EEG studies for the understanding of the pathogenesis of schizophrenic symptoms are presented. The basic assumptions of a heuristic and multifactorial model of the psychobiological brain mechanisms underlying the organization of normal behavior is described and used in order to formulate and test hypotheses about the pathogenesis of schizophrenic behavior using EEG measures. Results from our studies on EEG activity and EEG reactivity (= EEG components of a memory-driven, adaptive, non-unitary orienting response) as analyzed with spectral parameters and "chaotic" dimensionality (correlation dimension) are summarized. Both analysis procedures showed a deviant brain functional organization in never-treated first-episode schizophrenia which, within the framework of the model, suggests as common denominator for the pathogenesis of the symptoms a deviation of working memory, the nature of which is functional and not structural.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Psychiatric Neurophysiology (discontinued)

UniBE Contributor:

Federspiel, Andrea

ISSN:

0300-9564

ISBN:

8579811

Publisher:

Springer

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:55

Last Modified:

17 Mar 2015 22:01

Publisher DOI:

10.1007/BF01271472

PubMed ID:

8579811

Web of Science ID:

A1995QP02600008

URI:

https://boris.unibe.ch/id/eprint/23326 (FactScience: 41301)

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