[Does cataract surgery increase the risk of exudative age-related macular degeneration? Results from a large retrospective case-control study]

Menghini, M; Sutter, F K; Barthelmes, D; Fleischhauer, J C; Kurz-Levin, M M; Boesch, M M; Helbig, H (2007). [Does cataract surgery increase the risk of exudative age-related macular degeneration? Results from a large retrospective case-control study]. Klinische Monatsblätter für Augenheilkunde, 224(4), pp. 288-91. Stuttgart: Ferdinand Enke Verlag 10.1055/s-2007-962896

Full text not available from this repository.

BACKGROUND: Many epidemiological studies indicate a positive correlation between cataract surgery and the subsequent progression of age-related macular degeneration (AMD). Such a correlation would have far-reaching consequences. However, in epidemiological studies it is difficult to determine the significance of a single risk factor, such as cataract surgery. PATIENTS AND METHODS: We performed a retrospective case-control study of patients with new onset exudative age-related macular degeneration to determine if cataract surgery was a predisposing factor. A total of 1496 eyes were included in the study: 984 cases with new onset of exudative AMD and 512 control eyes with early signs of age-related maculopathy. Lens status (phakic or pseudophakic) was determined for each eye. RESULTS: There was no significant difference in lens status between study and control group (227/984 [23.1 %] vs. 112/512 [21.8 %] pseudophakic, p = 0.6487; OR = 1.071; 95 % CI = 0.8284-1.384). In cases with bilateral pseudophakia (n = 64) no statistically significant difference of the interval between cataract surgery in either eye and the onset of exudative AMD in the study eye was found (225.9 +/- 170.4 vs. 209.9 +/- 158.2 weeks, p = 0.27). CONCLUSIONS: Our results provide evidence that cataract surgery is not a major risk factor for the development of exudative AMD.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology
UniBE Contributor:	Fleischhauer, Johannes M.C.
ISSN:	0023-2165
ISBN:	17458794
Publisher:	Ferdinand Enke Verlag
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:55
Last Modified:	05 Dec 2022 14:17
Publisher DOI:	10.1055/s-2007-962896
PubMed ID:	17458794
Web of Science ID:	000246209700014
URI:	https://boris.unibe.ch/id/eprint/23579 (FactScience: 42586)