Boudny, Clara; Nievergelt, Helga; Braathen, Lasse R; Simon, Dagmar (2007). Wegener's granulomatosis presenting as pyoderma gangrenosum. Journal der Deutschen Dermatologischen Gesellschaft, 6(6), pp. 477-479. Berlin: Blackwell 10.1111/j.1610-0387.2007.06497.x
Full text not available from this repository.Half of the patients with Wegener's granulomatosis develop skin lesions due to the systemic vasculitis. Wegener's granulomatosis should be included in the differential diagnostic considerations for necrotic ulcers, including leg ulcers. We present a case which demonstrates the importance of histological evaluation of a skin biopsy from the margin of the ulcer for establishing the diagnosis. Antineutrophil cytoplasmic antibodies with antigen specificity for proteinase 3 (PR3-ANCA) were detected supporting the diagnosis of Wegener granulomatosis. Further evaluation showed involvement of the eyes and kidneys. The ulcer rapidly healed under treatment with cyclophosphamide and corticosteroids.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Nievergelt, Helga, Braathen, Lasse Roger, Simon, Dagmar |
ISSN: |
1610-0379 |
ISBN: |
18076660 |
Publisher: |
Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:56 |
Last Modified: |
05 Dec 2022 14:17 |
Publisher DOI: |
10.1111/j.1610-0387.2007.06497.x |
PubMed ID: |
18076660 |
Web of Science ID: |
000256802100007 |
URI: |
https://boris.unibe.ch/id/eprint/23726 (FactScience: 43788) |
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