Nutrition in clinical practice-the refeeding syndrome: illustrative cases and guidelines for prevention and treatment

Stanga, Z; Brunner, A; Leuenberger, M; Grimble, R F; Shenkin, A; Allison, S P; Lobo, D N (2008). Nutrition in clinical practice-the refeeding syndrome: illustrative cases and guidelines for prevention and treatment. European journal of clinical nutrition, 62(6), pp. 687-94. London: Nature Publishing Group 10.1038/sj.ejcn.1602854

Full text not available from this repository. (Request a copy)

The refeeding syndrome is a potentially lethal complication of refeeding in patients who are severely malnourished from whatever cause. Too rapid refeeding, particularly with carbohydrate may precipitate a number of metabolic and pathophysiological complications, which may adversely affect the cardiac, respiratory, haematological, hepatic and neuromuscular systems leading to clinical complications and even death. We aimed to review the development of the refeeding syndrome in a variety of situations and, from this and the literature, devise guidelines to prevent and treat the condition. We report seven cases illustrating different aspects of the refeeding syndrome and the measures used to treat it. The specific complications encountered, their physiological mechanisms, identification of patients at risk, and prevention and treatment are discussed. Each case developed one or more of the features of the refeeding syndrome including deficiencies and low plasma levels of potassium, phosphate, magnesium and thiamine combined with salt and water retention. These responded to specific interventions. In most cases, these abnormalities could have been anticipated and prevented. The main features of the refeeding syndrome are described with a protocol to anticipate, prevent and treat the condition in adults.

Item Type:

Journal Article (Original Article)

Division/Institute:

?? DCD5A442B9C7E17DE0405C82790C4DE2 ??
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Stanga, Zeno Giovanni and Leuenberger, Michèle Simone

ISSN:

0954-3007

ISBN:

17700652

Publisher:

Nature Publishing Group

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:56

Last Modified:

17 Mar 2015 22:03

Publisher DOI:

10.1038/sj.ejcn.1602854

PubMed ID:

17700652

Web of Science ID:

000256389600001

URI:

https://boris.unibe.ch/id/eprint/23784 (FactScience: 44411)

Actions (login required)

Edit item Edit item
Provide Feedback