Orbital manifestation of whipple's disease: an atypical case

Lieger, Olivier; Otto, Sven; Clemetson, Isabelle Ann; Arnold, Marlene; Iizuka, Tateyuki (2007). Orbital manifestation of whipple's disease: an atypical case. Journal of cranio-maxillo-facial surgery, 35(8), pp. 393-6. Oxford: Elsevier 10.1016/j.jcms.2007.03.005

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BACKGROUND: Whipple's disease is a systemic disorder caused by an infection with a gram-positive bacillus, Tropheryma whipplei. Almost every organ system can be affected in Whipple's disease, resulting in varying clinical symptoms. CASE REPORT: As far as we are aware, this report of a 61-year-old male is the first presenting with a periorbital manifestation of the disease, with severe exophthalmos and optic nerve involvement, leading to rapid visual loss. This emergency case was successfully treated by a surgical orbital decompression combined with systemic use of antibiotics and steroids. CONCLUSION: Whipple's disease can affect the periorbital tissues and the optic nerve, causing massive exophthalmos and serious transient visual loss. In such a case surgical decompression of the affected orbit combined with antibiotics and steroids is a recommended valid treatment option.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Craniomaxillofacial Surgery
UniBE Contributor:	Lieger, Olivier, Iizuka, Tateyuki
ISSN:	1010-5182
ISBN:	18029189
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:56
Last Modified:	05 Dec 2022 14:17
Publisher DOI:	10.1016/j.jcms.2007.03.005
PubMed ID:	18029189
Web of Science ID:	000252513600011
URI:	https://boris.unibe.ch/id/eprint/23812 (FactScience: 44491)