Unexpected metastatic pheochromocytoma - an unusual presentation

Birrenbach, Tanja; Stanga, Zeno; Cottagnoud, Philippe; Stucki, Armin (2008). Unexpected metastatic pheochromocytoma - an unusual presentation. European journal of internal medicine, 19(1), pp. 60-2. Roma: Pozzi 10.1016/j.ejim.2007.02.029

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The classic triad of pheochromocytoma consists of episodic headache, sweating, and tachycardia. General clinicians should be aware, however, that this rare entity might present with a wide spectrum of clinical symptoms. We recently observed a noteworthy case of malignant pheochromocytoma where there was a lack of specific symptoms despite an advanced tumor stage. Malignancy is an important cause of mortality. Reliable diagnosis of malignancy depends upon evidence of local invasion, distant metastases, or recurrence. As in our case, new scintigraphic methods, such as 111-In-pentetreotide scintigraphy (Octreoscan), may occasionally reveal 123-I-metaiodobenzylguanidine-negative distant metastases and help to establish an early diagnosis of malignancy. Tumor size, and perhaps even biochemical profile, may be factors increasing the likelihood of a malignant process and may contribute to early identification of patients at risk.

Item Type:

Journal Article (Original Article)

Division/Institute:

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04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine

UniBE Contributor:

Birrenbach, Tanja Nicole; Stanga, Zeno Giovanni; Cottagnoud, Philippe and Stucki, Armin Niklaus

ISSN:

0953-6205

ISBN:

18206604

Publisher:

Pozzi

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:56

Last Modified:

06 Dec 2013 13:47

Publisher DOI:

10.1016/j.ejim.2007.02.029

PubMed ID:

18206604

Web of Science ID:

000253274400011

URI:

https://boris.unibe.ch/id/eprint/23899 (FactScience: 45067)

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