Current state of the art in myocardial tissue engineering

Giraud, Marie-Noëlle; Armbruster, Christine; Carrel, Thierry; Tevaearai, Hendrik T (2007). Current state of the art in myocardial tissue engineering. Tissue engineering, 13(8), pp. 1825-36. Larchmont, N.Y.: Mary Ann Liebert 10.1089/ten.2006.0110

Full text not available from this repository. (Request a copy)

Myocardial tissue engineering aims to repair, replace, and regenerate damaged cardiac tissue using tissue constructs created ex vivo. This approach may one day provide a full treatment for several cardiac disorders, including congenital diseases or ventricular dysfunction after myocardial infarction. Although the ex vivo construction of a myocardium-like tissue is faced with many challenges, it is nevertheless a pressing objective for cardiac reparative medicine. Multidisciplinary efforts have already led to the development of promising viable muscle constructs. In this article, we review the various concepts of cardiac tissue engineering and their specific challenges. We also review the different types of existing biografts and their physiological relevance. Although many investigators have favored cardiomyocytes, we discuss the potential of other clinically relevant cells, as well as the various hypotheses proposed to explain the functional benefit of cell transplantation.

Item Type:

Journal Article (Further Contribution)


04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery

UniBE Contributor:

Giraud, Marie-Noelle, Armbruster, Christine, Carrel, Thierry, Tevaearai, Hendrik






Mary Ann Liebert




Factscience Import

Date Deposited:

04 Oct 2013 14:56

Last Modified:

05 Dec 2022 14:17

Publisher DOI:


PubMed ID:


Web of Science ID:


URI: (FactScience: 45418)

Actions (login required)

Edit item Edit item
Provide Feedback