The in vitro evidence for an effect of high homeopathic potencies--a systematic review of the literature

Witt, Claudia M; Bluth, Michael; Albrecht, Henning; Weisshuhn, Thorolf E R; Baumgartner, Stephan; Willich, Stefan N (2007). The in vitro evidence for an effect of high homeopathic potencies--a systematic review of the literature. Complementary therapies in medicine, 15(2), pp. 128-38. Exeter: Elsevier 10.1016/j.ctim.2007.01.011

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OBJECTIVE: Systematic assessment of the in vitro research on high potency effects. METHOD: Publications of experiments were collected through databases, experts, previous reviews, citation tracking. Inclusion criteria: stepwise agitated dilutions <10(-23); cells or molecules from human or animal. Experiments were assessed with the modified SAPEH score. RESULTS: From 75 publications, 67 experiments (1/3 of them replications) were evaluated. Nearly 3/4 of them found a high potency effect, and 2/3 of those 18 that scored 6 points or more and controlled contamination. Nearly 3/4 of all replications were positive. Design and experimental models of the reviewed experiments were inhomogenous, most were performed on basophiles. CONCLUSIONS: Even experiments with a high methodological standard could demonstrate an effect of high potencies. No positive result was stable enough to be reproduced by all investigators. A general adoption of succussed controls, randomization and blinding would strengthen the evidence of future experiments.

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Journal Article (Further Contribution)


04 Faculty of Medicine > Medical Education > Institute of Complementary and Integrative Medicine (IKIM)

UniBE Contributor:

Baumgartner, Stephan










Factscience Import

Date Deposited:

04 Oct 2013 14:56

Last Modified:

05 Dec 2022 14:17

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URI: (FactScience: 46227)

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