Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion

Chadjichristos, C E; Scheckenbach, K E L; van Veen, T A B; Richani Sarieddine, M Z; de Wit, C; Yang, Z; Roth, I; Bacchetta, M; Viswambharan, H; Foglia, B; Dudez, T; van Kempen, M J A; Coenjaerts, F E J; Miquerol, L; Deutsch, U; Jongsma, H J; Chanson, M; Kwak, B R (2010). Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion. Circulation, 121(1), pp. 123-31. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCULATIONAHA.109.867176

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Endothelial dysfunction is the initiating event of atherosclerosis. The expression of connexin40 (Cx40), an endothelial gap junction protein, is decreased during atherogenesis. In the present report, we sought to determine whether Cx40 contributes to the development of the disease.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Angiology
04 Faculty of Medicine > Pre-clinic Human Medicine > Theodor Kocher Institute

UniBE Contributor:

Yang, Zijiang and Deutsch, Urban

ISSN:

0009-7322

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:07

Last Modified:

04 May 2014 23:04

Publisher DOI:

10.1161/CIRCULATIONAHA.109.867176

PubMed ID:

20026782

Web of Science ID:

000273267700016

URI:

https://boris.unibe.ch/id/eprint/243 (FactScience: 197076)

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