A chromone from Seseli praecox (Apiaceae)

Leonti, Marco; Casu, Laura; Solinas, Maria Novella; Cottiglia, Filippo; Caboni, Pierluigi; Floris, Costantino; Gertsch, Juerg; Saba, Anna Rita (2010). A chromone from Seseli praecox (Apiaceae). Natural product communications, 5(4), pp. 551-4. Westerville, Ohio: Natural Product Communications NPC

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Chemical investigation of the stems of Seseli praecox (Gamisans) Gamisans, an endemic Apiaceae from Sardinia, afforded an isopropenylated chromone (5-hydroxy-6-(2-Z-butenyl-3-hydroxymethyl)-7-methoxy-2-methylchromone), along with four known linear furocoumarins and their natural precursor. For biological characterization the new compound was screened against four cancer cell lines in vitro and showed differential microM antiproliferative effects between suspension and adherent cells.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Biochemistry and Molecular Medicine

UniBE Contributor:

Gertsch, Jürg

ISSN:

1934-578X

Publisher:

Natural Product Communications NPC

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:12

Last Modified:

17 Mar 2015 19:14

PubMed ID:

20433070

Web of Science ID:

000276598500011

URI:

https://boris.unibe.ch/id/eprint/2437 (FactScience: 204936)

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