Pathomorphologic alterations predict presence or absence of hip osteoarthrosis

Ecker, Timo M; Tannast, Moritz; Puls, Marc; Siebenrock, Klaus A; Murphy, Stephen B (2007). Pathomorphologic alterations predict presence or absence of hip osteoarthrosis. Clinical orthopaedics and related research, 465, pp. 46-52. Heidelberg: Springer 10.1097/BLO.0b013e318159a998

Full text not available from this repository. (Request a copy)

Abnormal morphology of the hip has been associated with primary osteoarthrosis. We evaluated the morphology of 464 consecutive hips contralateral to hips treated by THA. We excluded all hips with known diagnoses leading to secondary osteoarthritis and all hips with advanced arthrosis to eliminate the effect of arthritic remodeling on the morphologic measurements. Of the remaining 119 hips, 25 were in patients aged 60 years or older who had no or mild arthrosis (Tönnis Grade 0 or 1) and 94 hips had Tönnis Grade 2 osteoarthrosis. We quantified morphologic parameters on plain radiographs and CT images and simulated range of motion using virtual bone models from the CT data. The nonarthritic hips had fewer pathomorphologic findings. High alpha angles and high lateral center edge angles were strongly associated with the presence of arthritis; decreased internal and external rotation in 90 degrees flexion showed lesser correlation. The data confirm previous observations that abnormal hip morphology predates arthrosis and is not secondary to the osteoarthritic process. Hips at risk for developing arthrosis resulting from pathomorphologic changes may potentially be identified at the cessation of growth, long before the development of osteoarthrosis.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Orthopaedic Surgery
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB [discontinued]

UniBE Contributor:

Ecker, Timo; Tannast, Moritz; Puls, Marc and Siebenrock, Klaus-Arno










Factscience Import

Date Deposited:

04 Oct 2013 14:57

Last Modified:

17 Mar 2015 22:05

Publisher DOI:


PubMed ID:


Web of Science ID:


URI: (FactScience: 50702)

Actions (login required)

Edit item Edit item
Provide Feedback