Clinical validation of electromyography and acceleromyography as sensors for muscle relaxation

Hänzi, P; Leibundgut, D; Wessendorf, R; Lauber, R; Zbinden, A M (2007). Clinical validation of electromyography and acceleromyography as sensors for muscle relaxation. European journal of anaesthesiology, 24(10), pp. 882-8. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1017/S0265021506002353

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BACKGROUND AND OBJECTIVE: The aim of this study was to determine which of two clinically applied methods, electromyography or acceleromyography, was less affected by external disturbances, had a higher sensitivity and which would provide the better input signal for closed loop control of muscle relaxation. METHODS: In 14 adult patients, anaesthesia was induced with intravenous opioids and propofol. The response of the thumb to ulnar nerve stimulation was recorded on the same arm. Mivacurium was used for neuromuscular blockade. Under stable conditions of relaxation, the infusion-rate was decreased and the effects of turning the hand were investigated. RESULTS: Electromyography and acceleromyography both reflected the change of the infusion rate (P = 0.015 and P < 0.001, respectively). Electromyography was significantly less affected by the hand-turn (P = 0.008) than acceleromyography. While zero counts were detected with acceleromyography, electromyography could still detect at least one count in 51.1%. CONCLUSIONS: Electromyography is more reliable for use in daily practice as it is less influenced by external disturbances than acceleromyography.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy

UniBE Contributor:

Leibundgut, Daniel and Lauber, Rolf






Lippincott Williams & Wilkins




Jeannie Wurz

Date Deposited:

04 Oct 2013 14:57

Last Modified:

23 Jan 2018 12:17

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Web of Science ID:


URI: (FactScience: 51533)

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