Genetic maps of the proximal half of chromosome arm 2L of Drosophila melanogaster

Levine, Sylvia; Sunday, Suchot; Dorig, Ruth; Suter, Beat; Lasko, Paul (2007). Genetic maps of the proximal half of chromosome arm 2L of Drosophila melanogaster. Genome, 50(2), pp. 137-41. Ottawa: National Research Council of Canada 10.1139/G06-149

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Drosophila mutants have played an important role in elucidating the physiologic function of genes. Large-scale projects have succeeded in producing mutations in a large proportion of Drosophila genes. Many mutant fly lines have also been produced through the efforts of individual laboratories over the past century. In an effort to make some of these mutants more useful to the research community, we systematically mapped a large number of mutations affecting genes in the proximal half of chromosome arm 2L to more precisely defined regions, defined by deficiency intervals, and, when possible, by individual complementation groups. To further analyze regions 36 and 39-40, we produced 11 new deficiencies with gamma irradiation, and we constructed 6 new deficiencies in region 30-33, using the DrosDel system. trans-heterozygous combinations of deficiencies revealed 5 additional functions, essential for viability or fertility.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Cell Biology

UniBE Contributor:

Suter, Beat (A)

ISSN:

0831-2796

Publisher:

National Research Council of Canada

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:57

Last Modified:

29 Mar 2023 23:33

Publisher DOI:

10.1139/G06-149

Web of Science ID:

000246961100003

URI:

https://boris.unibe.ch/id/eprint/24678 (FactScience: 52808)

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