Schindera, Sebastian T; Nelson, Rendon C; Paulson, Erik K; DeLong, David M; Merkle, Elmar M (2007). Assessment of the optimal temporal window for intravenous CT cholangiography. European radiology, 17(10), pp. 2531-7. Berlin: Springer 10.1007/s00330-007-0709-8
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The optimal temporal window of intravenous (IV) computed tomography (CT) cholangiography was prospectively determined. Fifteen volunteers (eight women, seven men; mean age, 38 years) underwent dynamic CT cholangiography. Two unenhanced images were acquired at the porta hepatis. Starting 5 min after initiation of IV contrast infusion (20 ml iodipamide meglumine 52%), 15 pairs of images at 5-min intervals were obtained. Attenuation of the extrahepatic bile duct (EBD) and the liver parenchyma was measured. Two readers graded visualization of the higher-order biliary branches. The first biliary opacification in the EBD occurred between 15 and 25 min (mean, 22.3 min +/- 3.2) after initiation of the contrast agent. Biliary attenuation plateaued between the 35- and the 75-min time points. Maximum hepatic parenchymal enhancement was 18.5 HU +/- 2.7. Twelve subjects demonstrated poor or non-visualization of higher-order biliary branches; three showed good or excellent visualization. Body weight and both biliary attenuation and visualization of the higher-order biliary branches correlated significantly (P<0.05). For peak enhancement of the biliary tree, CT cholangiography should be performed no earlier than 35 min after initiation of IV infusion. For a fixed contrast dose, superior visualization of the biliary system is achieved in subjects with lower body weight.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology |
UniBE Contributor: |
Schindera, Sebastian Tobias |
ISSN: |
0938-7994 |
ISBN: |
17609958 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:58 |
Last Modified: |
05 Dec 2022 14:18 |
Publisher DOI: |
10.1007/s00330-007-0709-8 |
PubMed ID: |
17609958 |
Web of Science ID: |
000249522900010 |
BORIS DOI: |
10.48350/24989 |
URI: |
https://boris.unibe.ch/id/eprint/24989 (FactScience: 54382) |
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