Transient raise of endothelin-1 plasma level and reduction of ocular blood flow in a patient with optic neuritis

Haufschild, T; Shaw, SG; Kaiser, HJ; Flammer, J (2003). Transient raise of endothelin-1 plasma level and reduction of ocular blood flow in a patient with optic neuritis. Ophthalmologica, 217(6), 451-3.. Basel: Karger 10.1159/000073079

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PURPOSE: To analyze how far an ischemic component might have been involved in optic neuritis. METHODS: Case report: a 32-year-old man with symptoms characteristic for optic neuritis underwent extensive clinical, laboratory/serological and vascular examination for systemic associations and vascular involvement. RESULTS: The patient was found to have a temporary ocular blood flow dysregulation and increased plasma endothelin-1 levels which decreased after the acute phase of the optic nerve. CONCLUSIONS: We conclude that there might be an ischemic component in this patient with optic neuritis and hypothesize that this ischemic component is at least in part due to a temporarily increased endothelin-1 level.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DCR Unit Tiefenau Hospital (discontinued) > Forschungsgruppe Vasoaktive Peptide (discontinued)

UniBE Contributor:

Shaw, Sidney

ISSN:

0030-3755

ISBN:

14573982

Publisher:

Karger

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:58

Last Modified:

04 May 2014 23:17

Publisher DOI:

10.1159/000073079

PubMed ID:

14573982

Web of Science ID:

000186459700014

URI:

https://boris.unibe.ch/id/eprint/25003 (FactScience: 54603)

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