Identification of brain structures involved in micturition with functional magnetic resonance imaging (fMRI)

Hruz, P; Lövblad, K O; Nirkko, A C; Thoeny, H; El-Koussy, M; Danuser, H (2008). Identification of brain structures involved in micturition with functional magnetic resonance imaging (fMRI). Journal of neuroradiology, 35(3), pp. 144-149. Issy-les-Moulineaux (F): Elsevier Masson 10.1016/j.neurad.2007.11.008

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OBJECTIVE: The voluntary control of micturition is believed to be integrated by complex interactions among the brainstem, subcortical areas and cortical areas. Several brain imaging studies using positron emission tomography (PET) have demonstrated that frontal brain areas, the limbic system, the pons and the premotor cortical areas were involved. However, the cortical and subcortical brain areas have not yet been precisely identified and their exact function is not yet completely understood. MATERIALS AND METHODS: This study used functional magnetic resonance imaging (fMRI) to compare brain activity during passive filling and emptying of the bladder. A cathetherism of the bladder was performed in seven healthy subjects (one man and six right-handed women). During scanning, the bladder was alternatively filled and emptied at a constant rate with bladder rincing solution. RESULTS: Comparison between passive filling of the bladder and emptying of the bladder showed an increased brain activity in the right inferior frontal gyrus, cerebellum, symmetrically in the operculum and mesial frontal. Subcortical areas were not evaluated. CONCLUSIONS: Our results suggest that several cortical brain areas are involved in the regulation of micturition.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology

UniBE Contributor:

Thöny, Harriet C. and El-Koussy, Marwan

ISSN:

0150-9861

ISBN:

18243317

Publisher:

Elsevier Masson

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:59

Last Modified:

08 Jun 2016 10:44

Publisher DOI:

10.1016/j.neurad.2007.11.008

PubMed ID:

18243317

Web of Science ID:

000258305200003

URI:

https://boris.unibe.ch/id/eprint/25445 (FactScience: 58575)

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