Pharmacotherapy, vaccines and malaria advice for HIV-infected travellers

Cavassini, ML; D'Acremont, V; Furrer, H; Genton, B; Tarr, PE (2005). Pharmacotherapy, vaccines and malaria advice for HIV-infected travellers. Expert opinion on pharmacotherapy, 6(6), pp. 891-913. London: Informa Healthcare 10.1517/14656566.6.891

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Since the introduction of effective antiretroviral therapy (ART), HIV-infected individuals are travelling more frequently and international travel has become much safer. Specific concerns include the safety of ART during travel, drug adherence and interaction considerations, and effects of immunosuppression. This review describes potentially important infections, vaccine effectiveness, safety and special approaches for their use, and HIV-related issues regarding predeparture counselling. With advanced immunosuppression (CD4+ T-cell count < 200/microl or < 14%), the immunogenicity of several vaccines is reduced, complications could occur after live attenuated vaccines and certain infections acquired during travel may be more frequent or severe. Challenges include the best options for malaria chemoprophylaxis, standby treatment and medical follow-up of the increasing number of HIV-infected long-term travellers.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Furrer, Hansjakob

ISSN:

1465-6566

ISBN:

15952919

Publisher:

Informa Healthcare

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:00

Last Modified:

17 Mar 2015 22:10

Publisher DOI:

10.1517/14656566.6.891

PubMed ID:

15952919

Web of Science ID:

000230944600004

URI:

https://boris.unibe.ch/id/eprint/25711 (FactScience: 60785)

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