Huang, Yiming; Enzmann, Volker; Ildstad, Suzanne T (2011). Stem cell-based therapeutic applications in retinal degenerative diseases. Stem cell reviews and reports, 7(2), pp. 434-45. New York, N.Y.: Springer 10.1007/s12015-010-9192-8
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Retinal degenerative diseases that target photoreceptors or the adjacent retinal pigment epithelium (RPE) affect millions of people worldwide. Retinal degeneration (RD) is found in many different forms of retinal diseases including retinitis pigmentosa (RP), age-related macular degeneration (AMD), diabetic retinopathy, cataracts, and glaucoma. Effective treatment for retinal degeneration has been widely investigated. Gene-replacement therapy has been shown to improve visual function in inherited retinal disease. However, this treatment was less effective with advanced disease. Stem cell-based therapy is being pursued as a potential alternative approach in the treatment of retinal degenerative diseases. In this review, we will focus on stem cell-based therapies in the pipeline and summarize progress in treatment of retinal degenerative disease.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Enzmann, Volker |
ISSN: |
1550-8943 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:12 |
Last Modified: |
05 Dec 2022 14:02 |
Publisher DOI: |
10.1007/s12015-010-9192-8 |
PubMed ID: |
20859770 |
Web of Science ID: |
000289297600019 |
BORIS DOI: |
10.48350/2646 |
URI: |
https://boris.unibe.ch/id/eprint/2646 (FactScience: 205491) |
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