[Vasculitis as a reason of chronic headache]

Ataia, I; Casaulta, C; von Vigier, R O; Pfammatter, J P; Brekenfeld, C; Sauvain, M J; Steinlin, M (2008). [Vasculitis as a reason of chronic headache]. Praxis - schweizerische Rundschau für Medizin, 97(6), pp. 322-5. Bern: Huber

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A 13-year-old girl presented to our emergency with a one week history of fever and skin rash and new onset of chorea for the last three days. There was a long standing history of right predominant headache; followed by personality change, fatigue, arthralgia and weight loss over the last few months. Previous investigations by head CT and ophthalmological examination did not explain the symptoms. Further investigations revealed peri- and pancarditis with aortic insufficiency, a renal involvement with elevated creatinin, protein- and hematuria and a hemolytic anemia. Diagnosis of lupus eythematodes was confirmed by high ANA, anti-dsDNS and Anticardiolipin antibodies. Within the first 48 hours after admission there was significant deterioration with reduced vigilance and dysarthria. MRI of the brain and dopplersonography of cerebral vessels showed a complete thrombosis of the right medial cerebral artery with a small net of collaterals, irregularities of the left cerebral artery due to vasculitis and several subacute leftsided ischemias. Immunosuppressive therapy with high-dose corticosteroids and cyclophosphamid together with antithrombotic therapy induced an improvement of neurologic, renal and cardiac function.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine 04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
UniBE Contributor:	Casaulta, Carmen, von Vigier, Rodo, Pfammatter, Jean-Pierre, Brekenfeld, Caspar, Sauvain, Marie-Josèphe, Steinlin, Maja
ISSN:	1661-8157
ISBN:	18548940
Publisher:	Huber
Language:	English
Submitter:	Anette van Dorland
Date Deposited:	04 Oct 2013 15:01
Last Modified:	02 Mar 2023 23:22
PubMed ID:	18548940
URI:	https://boris.unibe.ch/id/eprint/26694 (FactScience: 85916)