Noncompliance in organ transplant recipients: a literature review

Laederach-Hofmann, K; Bunzel, B (2000). Noncompliance in organ transplant recipients: a literature review. General hospital psychiatry, 22(6), pp. 412-24. New York, N.Y.: Elsevier 10.1016/S0163-8343(00)00098-0

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The consequences of failing to comply to doctor's instructions can be damaging and devastating for the individual patient and their family. Noncompliance also leads to waste, as it reduces the potential benefits of therapy, and to the extra cost of treating avoidable consequent morbidity. Life-long immunosuppression is a prerequisite for good graft function, and noncompliance is often associated with late acute rejection episodes, graft loss, and death. It might be assumed that transplant patients constitute a highly motivated group, and that compliance would be high. Unfortunately, this is not the case: overall noncompliance rates vary from 20 to 50%. This overview includes literature on heart, liver, and kidney transplants in adult and pediatric transplant patients. Compliance behavior after transplantation, noncompliance and its relationship to organ loss and death, retransplantation outcome after graft loss due to noncompliance, and reasons for postoperative noncompliance will be addressed.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition
UniBE Contributor:	Laederach, Kurt
ISSN:	0163-8343
ISBN:	11072057
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 15:01
Last Modified:	05 Dec 2022 14:19
Publisher DOI:	10.1016/S0163-8343(00)00098-0
PubMed ID:	11072057
Web of Science ID:	000165277500003
URI:	https://boris.unibe.ch/id/eprint/26708 (FactScience: 86982)