Dissociation of epileptic and inflammatory activity in Rasmussen Encephalitis

Hauf, Martinus; Wiest, Roland; Nirkko, Arto; Strozzi, Susi; Federspiel, Andrea (2009). Dissociation of epileptic and inflammatory activity in Rasmussen Encephalitis. Epilepsy research, 83(2-3), pp. 265-8. Amsterdam: Elsevier 10.1016/j.eplepsyres.2008.11.009

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SUMMARY: Multimodal imaging was performed in Rasmussen Encephalitis (RE) during episodes of complex-partial and focal motor status epilepticus including independent component analysis of BOLD-fMRI, arterial spin labeling perfusion imaging and diffusion tensor imaging. The active epileptic network and topographically independent brain areas showed regional hyperperfusion and progressive atrophy. The results suggest that hyperperfusion outside of the epileptic network represent active inflammation in RE and the imaging protocol presented here, allows assessing thereby the disease activity non-invasively.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Psychiatric Neurophysiology (discontinued)

UniBE Contributor:

Hauf, Martinus; Wiest, Roland; Nirkko, Arto C.; Strozzi, Susi and Federspiel, Andrea

ISSN:

0920-1211

ISBN:

19121924

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:02

Last Modified:

04 May 2014 23:18

Publisher DOI:

10.1016/j.eplepsyres.2008.11.009

PubMed ID:

19121924

Web of Science ID:

000263818400023

URI:

https://boris.unibe.ch/id/eprint/26891 (FactScience: 91711)

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