Long-term effects of supervised exercise training on walking capacity and quality of life in patients with intermittent claudication

Keo, H; Grob, E; Guggisberg, F; Widmer, J; Baumgartner, I; Schmid, J-P; Kalka, C; Saner, H (2008). Long-term effects of supervised exercise training on walking capacity and quality of life in patients with intermittent claudication. Vasa - European journal of vascular medicine, 37(3), pp. 250-6. Bern: Huber 10.1024/0301-1526.37.3.250

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Supervised exercise training has been shown to improve walking capacity in several studies of patients with intermittent claudication. However, data on long-term outcome are quite limited. The aim of this prospective study was to evaluate long-term effects of supervised exercise training on walking capacity and quality of life in patients with intermittent claudication. Patients and methods: Sixty-seven consecutive patients with intermittent claudication who completed a supervised 12-week exercise training program were asked for follow up evaluation 39 +/- 20 months after program completion. Pain-free walking distance (PWD) and maximum walking distances (MWD) were assessed by treadmill test and several questionnaires. Results: Forty (60%) patients agreed to participate, 22 (33%) refused participation, and 5 (7%) died during follow-up. PWD and MWD significantly improved at completion of 12-weeks supervised exercise training as compared to baseline (PWD 114 +/- 100 vs. 235 +/- 248, p = 0.002; MWD 297 +/- 273 vs. 474 +/- 359, p = 0.001). Improvement of PWD and MWD could be maintained at follow up (197 +/- 254, p = 0.014; 390 +/- 324, p = 0.035, respectively) with non-smokers showing significantly better sustained PWD and MWD improvement as compared to baseline. Overall, walking capacity correlated with functional status of quality of life. Conclusions: Major findings of this investigation were that improvement in walking capacity is sustained after completion of supervised exercise training program with best results in patients who quitted or never smoked. Improved walking capacity is associated with increased functional status of quality of life.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Angiology
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Keo, Hak Hong; Baumgartner, Iris; Schmid, Jean-Paul; Kalka, Christoph and Saner, Hugo

ISSN:

0301-1526

ISBN:

18690592

Publisher:

Huber

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:02

Last Modified:

04 May 2014 23:18

Publisher DOI:

10.1024/0301-1526.37.3.250

PubMed ID:

18690592

Web of Science ID:

000259576000006

URI:

https://boris.unibe.ch/id/eprint/26993 (FactScience: 99395)

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