Safety of drug-eluting stents

Windecker, Stephan; Jüni, Peter (2008). Safety of drug-eluting stents. Nature clinical practice - cardiovascular medicine, 5(6), pp. 316-28. Basingstoke, UK: Nature Publishing Group 10.1038/ncpcardio1189

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Drug-eluting stents (DESs) effectively reduce angiographic restenosis and the clinical need for repeat revascularization procedures as compared with bare-metal stents. Widely publicized concerns arose recently about the incidence of late and very late stent thrombosis with the use of first-generation DESs. Recent systematic reviews and large-scale registry studies demonstrated similar rates of overall mortality and myocardial infarction for patients treated with either DESs or bare-metal stents during long-term follow-up. Careful selection of stent type according to patient and lesion characteristics as well as monitoring of adherence to dual antiplatelet therapy could maximize the therapeutic potential of these devices. The purpose of the present Review is to provide the reader with an overview of the benefits and risks of first-generation DESs that could help physicians select the most appropriate stent type for each patient.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Windecker, Stephan and Jüni, Peter

ISSN:

1743-4297

ISBN:

18414453

Publisher:

Nature Publishing Group

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:02

Last Modified:

18 Jun 2015 15:45

Publisher DOI:

10.1038/ncpcardio1189

PubMed ID:

18414453

Web of Science ID:

000256098300010

BORIS DOI:

10.7892/boris.27016

URI:

https://boris.unibe.ch/id/eprint/27016 (FactScience: 99708)

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