Prior therapy influences the efficacy of lamivudine monotherapy in patients with lamivudine-resistant HIV-1 infection

Opravil, Milos; Klimkait, Thomas; Louvel, Severine; Wolf, Eva; Battegay, Manuel; Fux, Christoph A; Bernasconi, Enos; Vogel, Martin; Speck, Roberto; Weber, Rainer; Swiss HIV Cohort Study, (2010). Prior therapy influences the efficacy of lamivudine monotherapy in patients with lamivudine-resistant HIV-1 infection. Journal of acquired immune deficiency syndromes JAIDS, 54(1), pp. 51-8. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/QAI.0b013e3181bef889

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The M184V mutation decreases the replication capacity of HIV-1. This prospective study aimed to characterize the virologic and immunologic changes during monotherapy with lamivudine (3TC) in patients with limited options for a fully suppressive new therapy.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Fux, Christoph Andreas

ISSN:

0894-9255

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:13

Last Modified:

17 Mar 2015 19:15

Publisher DOI:

10.1097/QAI.0b013e3181bef889

PubMed ID:

19838125

Web of Science ID:

000277001500007

URI:

https://boris.unibe.ch/id/eprint/2717 (FactScience: 205585)

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