Selective retina therapy (SRT) in patients with geographic atrophy due to age-related macular degeneration

Prahs, Philipp; Walter, Andreas; Regler, Roman; Theisen-Kunde, Dirk; Birngruber, Reginald; Brinkmann, Ralf; Framme, Carsten (2010). Selective retina therapy (SRT) in patients with geographic atrophy due to age-related macular degeneration. Graefe's archive for clinical and experimental ophthalmology, 248(5), pp. 651-8. Berlin: Springer 10.1007/s00417-009-1208-1

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For geographic atrophy (GA) due to age-related macular degeneration (AMD) there is so far no approved treatment option. Usually, increased autofluorescence (AF) levels of different patterns adjacent to the atrophic area indicate lipofuscin-laden retinal pigment epithelium (RPE) cells at a high risk for apoptosis. Herein, SRT was used to selectively treat these cells to stimulate RPE proliferation, in order to reduce or ideally stop further growth of the atrophic area.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Framme, Carsten Karl Josef

ISSN:

0721-832X

Publisher:

Springer

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:07

Last Modified:

06 Dec 2013 13:19

Publisher DOI:

10.1007/s00417-009-1208-1

PubMed ID:

20024687

Web of Science ID:

000276071100005

URI:

https://boris.unibe.ch/id/eprint/273 (FactScience: 197258)

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