Absence of prosthesis-patient mismatch with the new generation of Edwards stented aortic bioprosthesis

Wyss, Thomas R; Bigler, Marc; Stalder, Mario; Englberger, Lars; Aymard, Thierry; Kadner, Alexander; Carrel, Thierry P (2010). Absence of prosthesis-patient mismatch with the new generation of Edwards stented aortic bioprosthesis. Interactive cardiovascular and thoracic surgery, 10(6), 884-7; discussion 887-8. Oxford: Oxford University Press 10.1510/icvts.2009.224915

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Prosthesis-patient mismatch (PPM) remains a controversial issue with the most recent stented biological valves. We analyzed the incidence of PPM after implantation of the Carpentier-Edwards Perimount Magna Ease aortic valve (PMEAV) bioprosthesis and assessed the early clinical outcome. Two hundred and seventy consecutive patients who received a PMEAV bioprosthesis between January 2007 and July 2008 were analyzed. Pre-, peri- and postoperative data were assessed and echocardiographic as well as clinical follow-up was performed. Mean age was 72+/-9 years, 168 (62.2%) were males. Fifty-seven patients (21.1%) were below 65 years of age. Absence of PPM, corresponding to an indexed effective orifice area >0.85 cm(2)/m(2), was 99.5%. Observed in-hospital mortality was 2.2% (six patients), with a predicted mortality according to the additive EuroSCORE of 7.6+/-3.1%. At echocardiographic assessment after a mean follow-up period of 150+/-91 days, mean transvalvular gradient was 11.8+/-4.8 mmHg (all valve sizes). No paravalvular leakage was seen. Nine patients died during follow-up. The Carpentier-Edwards PMEAV bioprosthesis shows excellent hemodynamic performance. This valve can be implanted in all sizes with an incidence of severe PPM below 0.5%.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Heart Surgery

UniBE Contributor:

Wyss, Thomas Rudolf, Bigler, Marc, Stalder, Mario, Englberger, Lars, Aymard, Thierry, Kadner, Alexander, Carrel, Thierry




Oxford University Press




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Date Deposited:

04 Oct 2013 14:13

Last Modified:

27 Feb 2024 14:29

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https://boris.unibe.ch/id/eprint/2734 (FactScience: 205607)

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