Brinks, Henriette; Boucher, Matthieu; Gao, Erhe; Chuprun, J Kurt; Pesant, Stéphanie; Raake, Philip W; Huang, Z Maggie; Wang, Xiaoliang; Qiu, Gang; Gumpert, Anna; Harris, David M; Eckhart, Andrea D; Most, Patrick; Koch, Walter J (2010). Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms. Circulation research, 107(9), pp. 1140-9. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.110.221010
Full text not available from this repository.Activation of prosurvival kinases and subsequent nitric oxide (NO) production by certain G protein-coupled receptors (GPCRs) protects myocardium in ischemia/reperfusion injury (I/R) models. GPCR signaling pathways are regulated by GPCR kinases (GRKs), and GRK2 has been shown to be a critical molecule in normal and pathological cardiac function.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Heart Surgery |
UniBE Contributor: |
Most, Henriette |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0009-7330 |
Publisher: |
Lippincott Williams & Wilkins |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:13 |
Last Modified: |
27 Feb 2024 14:29 |
Publisher DOI: |
10.1161/CIRCRESAHA.110.221010 |
PubMed ID: |
20814022 |
Web of Science ID: |
000283583400014 |
URI: |
https://boris.unibe.ch/id/eprint/2748 (FactScience: 205622) |
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