High-dose intravenous corticosteroid pulse therapy in alopecia areata: own experience compared with the literature

Luggen, Peter; Hunziker, Thomas (2008). High-dose intravenous corticosteroid pulse therapy in alopecia areata: own experience compared with the literature. Journal der Deutschen Dermatologischen Gesellschaft, 6(5), pp. 375-8. Berlin: Blackwell 10.1111/j.1610-0387.2007.06608.x

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BACKGROUND: Seven prospective studies including 193 patients have been published on high-dose intravenous corticosteroid pulse therapy in alopecia areata (AA).We compare these data with a retrospective analysis of our own consecutive patients. PATIENTS AND METHODS: Between 1998 and 2002,25 patients with severe AA were treated at the Department of Dermatology, University of Bern, with infusions of 500 mg methylprednisolone on 3 consecutive days.In addition to the inpatient records, in 2004 all patients were followed up by a questionnaire. RESULTS: Four of 10 patients with multifocal AA and 3 of 9 patients with ophiasis-type AA had full re-growth of hair, whereas all 6 patients with AA totalis/universalis failed to respond. CONCLUSION: Intravenous corticosteroid pulse therapy may be helpful in the treatment of multifocal and ophiasis-type AA. Patients with an initial episode of short duration have better chances for success.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Hunziker, Thomas

ISSN:

1610-0379

ISBN:

18205838

Publisher:

Blackwell

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:04

Last Modified:

04 May 2014 23:19

Publisher DOI:

10.1111/j.1610-0387.2007.06608.x

PubMed ID:

18205838

Web of Science ID:

000255839700006

URI:

https://boris.unibe.ch/id/eprint/27637 (FactScience: 109751)

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