Influence of Smoothing on Voxel-Based Mesh Accuracy in Micro-Finite Element

Bardyn, Thibaut; Reyes, Mauricio; Larrea, Xabier; Büchler, Philippe (2010). Influence of Smoothing on Voxel-Based Mesh Accuracy in Micro-Finite Element. In: Miller, Karol; Nielsen, Pourl M F (eds.) Computational Biomechanics for Medicine (pp. 85-93). New York: Springer 10.1007/978-1-4419-5874-7_10

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The interest in automatic volume meshing for finite element analysis (FEA) has grown more since the appearance of microfocus CT (μCT), due to its high resolution, which allows for the assessment of mechanical behaviour at a high precision. Nevertheless, the basic meshing approach of generating one hexahedron per voxel produces jagged edges. To prevent this effect, smoothing algorithms have been introduced to enhance the topology of the mesh. However, whether smoothing also improves the accuracy of voxel-based meshes in clinical applications is still under question. There is a trade-off between smoothing and quality of elements in the mesh. Distorted elements may be produced by excessive smoothing and reduce accuracy of the mesh. In the present work, influence of smoothing on the accuracy of voxel-based meshes in micro-FE was assessed. An accurate 3D model of a trabecular structure with known apparent mechanical properties was used as a reference model. Virtual CT scans of this reference model (with resolutions of 16, 32 and 64 μm) were then created and used to build voxel-based meshes of the microarchitecture. Effects of smoothing on the apparent mechanical properties of the voxel-based meshes as compared to the reference model were evaluated. Apparent Young’s moduli of the smooth voxel-based mesh were significantly closer to those of the reference model for the 16 and 32 μm resolutions. Improvements were not significant for the 64 μm, due to loss of trabecular connectivity in the model. This study shows that smoothing offers a real benefit to voxel-based meshes used in micro-FE. It might also broaden voxel-based meshing to other biomechanical domains where it was not used previously due to lack of accuracy. As an example, this work will be used in the framework of the European project ContraCancrum, which aims at providing a patient-specific simulation of tumour development in brain and lungs for oncologists. For this type of clinical application, such a fast, automatic, and accurate generation of the mesh is of great benefit.

Item Type:

Book Section (Book Chapter)


04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB [discontinued]

UniBE Contributor:

Bardyn, Thibaut, Reyes Aguirre, Mauricio Antonio, Larrea, Xabier, Büchler, Philippe


500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health








Mauricio Antonio Reyes Aguirre

Date Deposited:

04 Oct 2013 14:13

Last Modified:

02 Mar 2023 23:20

Publisher DOI:


Web of Science ID:


URI: (FactScience: 205715)

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